Using this method, there is the potential to grow human organs in a shorter time frame than occurs in humans, due to the shorter gestational period of pigs. Additionally, if this new research leads to success in practice, some fear that this could eventually lead to growing human fetuses with the intent of harvesting their organs.

But some people worry about blurring the lines between humans and animals. If you tend more toward science-fiction dystopias, though, the prospect of breeding pigs with human organs presents some ethical concerns, to say the least.

, however, could use stem cells from the future organ recipient in the pig embryo, which could create an organ that would be a better match than what is achievable with traditional transplant methods.

While some research has focused on sheep, pigs happen to make excellent hosts for human organs. “The basic impetus behind this research is the sort of holy grail of regenerative medicine— to help us replace our body parts when they’re sick or diseased,” Amy Hinterberger, a sociologist at the University of Warwick who specializes in human–animal chimera research, told BuzzFeed News. Another was that human embryos have a much longer gestation time than pigs, which are born after just 114 days.

Supporters of the research contend that it is worth the risks as long as human lives could be saved. The team then took stem cells from rats and injected them into pig blastocysts.

But what if we could change that by growing our own? But this is a technical problem that can be tackled in a targeted and rational way.”. The technique could be put to use much sooner as a way to study human embryo development and understand disease. However, there is also quite a bit of controversy surrounding the ethics of using pigs as biological incubators for human organs.

Additionally, there are ethical concerns to using pigs as biological incubators for human organs. These pigs would be bred for the sole purpose of growing organs before being killed to harvest the organs for donation. The resulting human-animal chimeras don’t grow well, and few human cells survive. If this research is successful, it would mean that human organs could be grown inside of live pigs for future harvest and organ donation. These include various anatomic and physiologic traits, such as organ placement (and often size and function), skin similarities and some disease progression. Internal Organs.

The concept of chimeras predates human attempts to artificially create them, and at a basic level refers to an organism with tissue that comes from two or more different zygotes, the little cells that form after sperm fertilizes egg (in mammals). Room-temperature superconductivity has been achieved for the first time, A man caught coronavirus twice—and it was worse the second time, Inside Singapore’s huge bet on vertical farming.

The newly published work was carried out in the lab of Juan Carlos Izpisua Belmonte, a Salk Institute scientist who specializes in studying embryos and cells derived from them.

While labs have previously created human–animal chimeras, such as mice transplanted with human cancer cells or immune systems or even brain cells, these new experiments, published in the journal Cell, are unique because they place human stem cells — which can grow to become any of the different types of cells in the human body — into animal embryos at their earliest stages of life.

That sounds promising, but so far human cells don’t mix as readily with those of other animals.

Become a BuzzFeed News member. Between 1902 and 1923, organs from pigs, goats, sheep, and monkeys were used in unsuccessful transplantation attempts.

There's also a concern based more in science fiction than reality, but here goes: What if those human cells somehow migrate to the developing pig's brain and make it more human?

According to the American Transplant Foundation, 22 people die everyday waiting for organ donations. The researchers saw signs of human cells, but they were rare. The embryo is then implanted into a sow. The technology involves combining versatile stem cells from one species into the early embryo of another, when it is a ball of just 150 or so cells. Could Pigs Be Used to Grow Human Organs for Transplant?

However, there is also quite a bit of controversy surrounding the ethics of using pigs as biological incubators for human organs. The trick works in rats and mice: Yesterday researchers reported in Nature that they had grown a pancreas made of mouse cells inside a rat, and that the tissue could cure diabetes when it was transplanted back into a sick mouse. Still, that he and his colleagues found surviving human cells at all after 4 weeks of development is “remarkable,” he says.

Human stem cells being injected into a pig embryo. Nakauchi called the results “essentially negative” and consistent with experiments he has also carried out on human-animal hybrids.

Supporters of the research contend that it is worth the risks as long as human lives could be saved.

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